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  • ABOUT US
  • Services
    • SERVICE OVERVIEW
    • Osteoarthritis models
    • Cartilage regen. models
    • Bone regen. models
    • Tendon regen. models
    • Vector Library Screening
  • CONTACT
  • LEADERS
  • TARGETS
  • Papers
  • Mehr
    • HOME
    • ABOUT US
    • Services
      • SERVICE OVERVIEW
      • Osteoarthritis models
      • Cartilage regen. models
      • Bone regen. models
      • Tendon regen. models
      • Vector Library Screening
    • CONTACT
    • LEADERS
    • TARGETS
    • Papers
  • HOME
  • ABOUT US
  • Services
    • SERVICE OVERVIEW
    • Osteoarthritis models
    • Cartilage regen. models
    • Bone regen. models
    • Tendon regen. models
    • Vector Library Screening
  • CONTACT
  • LEADERS
  • TARGETS
  • Papers

About Lunatum Biotech - your preclinical CRO

Lunatum Biotech stands as your premier preclinical CRO partner in musculoskeletal drug discovery, dedicated to advancing your preclinical development endeavors for therapies targeting joints, cartilage, bone, tendon, and muscle diseases. Leveraging our unparalleled expertise and extensive network, we empower you to navigate the complexities of both rare and common musculoskeletal disorders, guiding the path towards innovative treatment solutions.

Attention molecular therapy and gene delivery system developers seeking novel therapeutic avenues with significant unmet needs: Explore the promising realm of musculoskeletal medicine with Lunatum Biotech - your preclinical CRO orthopedics. In a market ripe with opportunities and a pressing demand for effective molecular and  gene therapy treatments, our seasoned and specialized scientists stand ready to collaborate with you. Each of our scientists has at least 20+ years of experience in musculoskeletal gene medicine. Together, we'll identify compelling disease indications for your technology and pioneer life-changing therapies for patients battling debilitating musculoskeletal conditions. Join us in shaping the future of medicine and making a tangible difference in patients' lives.



Our Services

Why choose us?



Our expertise and experience

Lunatum Biotech is your reliable and innovative preclinical CRO orthopedics and partner for preclinical research and development in the field of molecular musculoskeletal medicine and gene therapy. Our scientists use optimized techniques and work protocols for the isolation and in-depth analysis of on-target and off-target cells. Using a variety of innovative in-vitro modeling systems and in-vivo musculoskeletal research models, we provide crucial preclinical insights to companies working towards developing targeted drugs for the rapidly expanding orthopedic gene medicine market. 



Our specialization and commitment

Lunatum Biotech offers a comprehensive solution for the preclinical evaluation of pioneering therapy approaches, serving as your premier partner in advancing medical progress. With expertise spanning the medical fields of orthopedics and sports medicine, trauma and reconstructive surgery, and rheumatology, we are committed to addressing the unmet needs of the pharmaceutical and biotech industry. At Lunatum, we aim to play a pivotal role in propelling the field of musculoskeletal therapies forward.



Our motivation and communication

At Lunatum Biotech, we prioritize direct collaboration between our clients and seasoned lead scientists, ensuring responsive and transparent communication at every step of the project. Our hallmark is delivering scientific excellence promptly and within budget, setting us apart in the industry. With a team of highly motivated scientists who deeply comprehend your requirements, we are dedicated to advancing both your scientific goals and commercial success. Partner with Lunatum Biotech for a seamless journey towards achieving your objectives.

The services of Lunatum Biotech:

Selected models (but not limited to):


  • Osteoarthritis models - CRO osteoarthritis
  • Cartilage regeneration models - CRO cartilage
  • Bone regeneration models - CRO bone
  • Tendinopathy / tendon injury models - CRO tendon

                                          

Selected service packages:


  • Vector library screening and single vector testing - CRO gene therapy


Our array of preclinical CRO services encompasses:


  • consulting on potential applications of your technology in the field of musculoskeletal medicine
  • advising on market opportunities and therapeutic needs
  • consulting / developing project designs
  • preparing animal protocols 
  • creating in-vitro and in-vivo models
  • conducting preclinical in vitro and in vivo experiments
  • determination of transduction/transfection using cartilage cells, synovium cells, bone cells, tendon cells from various species -including human cells 
  • proof-of-concept studies, biodistribution studies, pharmacokinetics, safety evaluation, efficacy studies
  • providing a comprehensive portfolio of established animal models as well as in-vitro modeling systems 
  • detailed data analysis
  • data reporting


We possess unparalleled preclinical CRO expertise regarding the following target tissues/organs:


  • joints 
  • cartilage
  • bone
  • tendon
  • muscle
  • intervertebral disc


We employ a variety of experimental methods, 

such as:


  • creation of sophisticated, valid, and reliable research models (in vitro and in vivo)
  • use of surgical and non-surgical animal models (small and large)
  • precise and reproducible surgical procedures
  • local and systemic administration of viral and non-viral vectors
  • in depths analysis of on-target and off-target cells and tissues
  • optimized cell isolation and purification
  • DNA/RNA extraction
  • Polymerase Chain Reaction (PCR)
  • Next Generation Sequencing (NGS)
  • histological evaluation, histopathology
  • immunohistochemistry
  • histomorphometry
  • various imaging techniques: IVIS, x-ray, CT, MRI
  • biomechanical testing
  • behavioral tests: pain evaluation, gait analysis
  • scoring/assessment: images, behaviour


Contact us for further details regarding our continuously expanding orthopedic CRO services.

Musculoskeletal Diseases

The disorders listed below provide valuable insight into the numerous unmet treatment needs within musculoskeletal diseases. Please don't hesitate to contact us for in-depth discussions about target diseases, areas of research interests, and how Lunatum Biotech can offer support in developing cures for these conditions. We are deeply committed to collaborating with you to make significant strides in the field of musculoskeletal medicine. Our special focus is on CRO osteoarthritis and CRO bone services.

Joints and Rheumatic Joint Disorders

Osteoarthritis, Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis - Lunatum Biotech is a preclinical CRO orthopedics with a special focus on CRO osteoarthritis services.

Cartilage

Osteoarthritis, cartilage defects, osteochondral defects, Diastrophic Dysplasia - Lunatum Biotech is a preclinical CRO orthopedics with a special focus on CRO osteoarthritis services.

Bone

Osteoporosis, Osteogenesis Imperfecta (OI), Fibrous Dysplasia, Hypophosphatasia, Fibrodysplasia Ossificans Progressiva (FOP), Multiple Epiphyseal Dysplasia (MED), Osteonecrosis, bone tumors, bone metastasis, bone fractures, osseous non-unions, bone defects - Lunatum Biotech is a preclinical CRO orthopedics with a special focus on CRO bone services.

Tendon and Ligament

Tendon ruptures, Tendinitis, chronic tendon degeneration, ligament tears

Muscle and Rheumatic Muscle Diseases

Sarcopenia, Duchenne Muscular Dystrophy, Myasthenia Gravis, Spinal Muscular Atrophy, Polymyalgia Rheumatica, Polymyositis, muscle injuries

Intervertebral Disc

Intervertebral Disc Disease

Leadership - LUNATUM BIOTECH, LLC - YOUR PRECLINICAL CRO

Oliver B. Betz, PhD

Oliver is the Chief Executive Officer and founder of Lunatum Biotech, LLC - your preclinical CRO; he received post-doctoral training at Harvard Medical School and was an Instructor at the Center for Molecular Orthopedics; Oliver served as Head of Orthopedic Regenerative Medicine at the University of Munich LMU and was a Visiting Scientist at MIT; he has 25 + years of experience in musculoskeletal research and gene medicine.

Fawzy A. Saad, PhD

Fawzy serves as Chief Scientific Officer of Lunatum Biotech, LLC - your preclinical CRO; he received post-doctoral training at Harvard Medical School and was an Assistant Professor at Einstein College of Medicine; Fawzy has 25 + years of experience in molecular musculoskeletal medicine.

Volker M. Betz, MD

Volker is the Medical Director of Lunatum Biotech, LLC - your preclinical CRO; he received post-doctoral training at Harvard Medical School; Volker is an Orthopedic Surgeon and a passionate scientist; he has 20 + years of experience in orthopedic research and gene therapy

Contact Us

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Lunatum Biotech, LLC - your preclinical CRO orthopedics with a special focus on CRO osteoarthritis and CRO bone services


Please send us a message or call us!

 

Lunatum Biotech´s phone number:  

(+1) 781 518 8894


Lunatum Biotech´s Email:

info@lunatumbiotech.com


Lunatum Biotech´s address:

100 Cummings Center, Suite 451C

Beverly, MA 01915

USA

Lunatum Biotech, LLC


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