Welcome to
Lunatum Biotech - your preclinical CRO for orthopedic gene medicine
Preclinical CRO experts for joints, cartilage, bone, and tendon - with a focus on osteoarthritis and rare bone diseases
About us
"Lunatum Biotech’s expertise in musculoskeletal research, particularly in osteoarthritis, has been invaluable to us. Their use of advanced models and innovative approaches—integrating behavioral studies, imaging, and post-mortem analyses—delivers unparalleled insights into treatment efficacy. Their precision, scientific rigor, and transparency make them a trusted partner in advancing our projects. The Lunatum team was always mindful of our budget and consistently available for questions or updates."
Mari Anne Snow, CEO of
EASCRA BIOTECH, Inc.,
MassBioDrive Startup of the Year,
NASA and ISS National Lab
sponsored research on the ISS
Lunatum Biotech is your trusted partner in musculoskeletal drug discovery, specializing in preclinical development for joint, cartilage, bone, tendon, and muscle diseases. With decades of expertise and a focus on innovation, we help navigate the complexities of rare and common musculoskeletal disorders to develop impactful therapies.
For molecular therapy and gene delivery system developers, the growing field of musculoskeletal medicine offers vast opportunities. Our expert team, each with 20+ years in gene medicine, collaborates with you to identify high-impact disease indications and drive breakthroughs in treatment. Together, let's transform patient care and shape the future of medicine.
Our Services
Why choose us?
Our expertise and experience
Lunatum Biotech is your reliable and innovative preclinical CRO and partner for preclinical research and development in the field of molecular musculoskeletal medicine and gene therapy. Our scientists use optimized techniques and work protocols for the isolation and in-depth analysis of on-target and off-target cells. Using a variety of innovative in-vitro modeling systems and in-vivo musculoskeletal research models, we provide crucial preclinical insights to companies working towards developing targeted drugs for the rapidly expanding orthopedic gene medicine market.
Our specialization and commitment
Lunatum Biotech offers a comprehensive solution for the preclinical evaluation of pioneering therapy approaches, serving as your premier partner in advancing medical progress. With expertise spanning the medical fields of orthopedics and sports medicine, trauma and reconstructive surgery, and rheumatology, we are committed to addressing the unmet needs of the pharmaceutical and biotech industry. At Lunatum, we aim to play a pivotal role in propelling the field of musculoskeletal therapies forward.
Our motivation and communication
At Lunatum Biotech, we prioritize direct collaboration between our clients and seasoned lead scientists, ensuring responsive and transparent communication at every step of the project. Our hallmark is delivering scientific excellence promptly and within budget, setting us apart in the industry. With a team of highly motivated scientists who deeply comprehend your requirements, we are dedicated to advancing both your scientific goals and commercial success. Partner with Lunatum Biotech for a seamless journey towards achieving your objectives.
The services of Lunatum Biotech:
Selected models (but not limited to):
- Osteoarthritis models
- Cartilage regeneration models
- Bone regeneration models
- Tendinopathy / tendon injury models
Selected service packages:
Our array of services encompasses:
- consulting on potential applications of your technology in the field of musculoskeletal medicine
- advising on market opportunities and therapeutic needs
- consulting / developing project designs
- preparing animal protocols
- creating in-vitro and in-vivo models
- conducting preclinical in vitro and in vivo experiments
- determination of transduction/transfection using cartilage cells, synovium cells, bone cells, tendon cells from various species -including human cells
- proof-of-concept studies, biodistribution studies, pharmacokinetics, safety evaluation, efficacy studies
- providing a comprehensive portfolio of established animal models as well as in-vitro modeling systems
- detailed data analysis
- data reporting
We possess unparalleled expertise regarding the following target tissues/organs:
- joints
- cartilage
- bone
- tendon
- muscle
- intervertebral disc
We employ a variety of experimental methods, such as:
- creation of sophisticated, valid, and reliable research models (in vitro and in vivo)
- use of surgical and non-surgical animal models (small and large)
- precise and reproducible surgical procedures
- local and systemic administration of viral and non-viral vectors
- in depths analysis of on-target and off-target cells and tissues
- optimized cell isolation and purification
- DNA/RNA extraction
- Polymerase Chain Reaction (PCR)
- Next Generation Sequencing (NGS)
- histological evaluation, histopathology
- immunohistochemistry
- histomorphometry
- various imaging techniques: IVIS, x-ray, CT, MRI
- biomechanical testing
- behavioral tests: pain evaluation, gait analysis
- scoring/assessment: images, behaviour
Contact us for further details regarding our continuously expanding services.
Musculoskeletal Diseases
The disorders listed below provide valuable insight into the numerous unmet treatment needs within musculoskeletal diseases. Please don't hesitate to contact us for in-depth discussions about target diseases, areas of research interests, and how Lunatum Biotech can offer support in developing cures for these conditions. We are deeply committed to collaborating with you to make significant strides in the field of musculoskeletal medicine.
Joints and Rheumatic Joint Disorders
Osteoarthritis, Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
Cartilage
Osteoarthritis, cartilage defects, osteochondral defects, Diastrophic Dysplasia
Bone
Osteoporosis, Osteogenesis Imperfecta (OI), Fibrous Dysplasia, Hypophosphatasia, Fibrodysplasia Ossificans Progressiva (FOP), Multiple Epiphyseal Dysplasia (MED), Osteonecrosis, bone tumors, bone metastasis, bone fractures, osseous non-unions, bone defects
Tendon and Ligament
Tendon ruptures, Tendinitis, Tendinopathy, chronic tendon degeneration, ligament tears
Muscle and Rheumatic Muscle Diseases
Sarcopenia, Duchenne Muscular Dystrophy, Myasthenia Gravis, Spinal Muscular Atrophy, Polymyalgia Rheumatica, Polymyositis, muscle injuries
Intervertebral Disc
Intervertebral Disc Disease