Welcome to
Lunatum Biotech - your preclinical CRO for orthopedic gene medicine
R&D experts for joints, cartilage, bone, and tendon - with a focus on osteoarthritis and rare bone diseases
About us
Lunatum Biotech stands as your premier partner in musculoskeletal drug discovery, dedicated to advancing your preclinical development endeavors for therapies targeting joints, cartilage, bone, tendon, and muscle diseases. Leveraging our unparalleled expertise and extensive network, we empower you to navigate the complexities of both rare and common musculoskeletal disorders, guiding the path towards innovative treatment solutions.
Attention molecular therapy and gene delivery system developers seeking novel therapeutic avenues with significant unmet needs: Explore the promising realm of musculoskeletal medicine with Lunatum Biotech! In a market ripe with opportunities and a pressing demand for effective molecular and gene therapy treatments, our seasoned and specialized scientists stand ready to collaborate with you. Each of our scientists has at least 20+ years of experience in musculoskeletal gene medicine. Together, we'll identify compelling disease indications for your technology and pioneer life-changing therapies for patients battling debilitating musculoskeletal conditions. Join us in shaping the future of medicine and making a tangible difference in patients' lives.
Our Services
Why choose us?
Our expertise and experience
Lunatum Biotech is your reliable and innovative preclinical CRO and partner for preclinical research and development in the field of molecular musculoskeletal medicine and gene therapy. Our scientists use optimized techniques and work protocols for the isolation and in-depth analysis of on-target and off-target cells. Using a variety of innovative in-vitro modeling systems and in-vivo musculoskeletal research models, we provide crucial preclinical insights to companies working towards developing targeted drugs for the rapidly expanding orthopedic gene medicine market.
Our specialization and commitment
Lunatum Biotech offers a comprehensive solution for the preclinical evaluation of pioneering therapy approaches, serving as your premier partner in advancing medical progress. With expertise spanning the medical fields of orthopedics and sports medicine, trauma and reconstructive surgery, and rheumatology, we are committed to addressing the unmet needs of the pharmaceutical and biotech industry. At Lunatum, we aim to play a pivotal role in propelling the field of musculoskeletal therapies forward.
Our motivation and communication
At Lunatum Biotech, we prioritize direct collaboration between our clients and seasoned lead scientists, ensuring responsive and transparent communication at every step of the project. Our hallmark is delivering scientific excellence promptly and within budget, setting us apart in the industry. With a team of highly motivated scientists who deeply comprehend your requirements, we are dedicated to advancing both your scientific goals and commercial success. Partner with Lunatum Biotech for a seamless journey towards achieving your objectives.
The services of Lunatum Biotech:
Selected models (but not limited to):
- Osteoarthritis models
- Cartilage regeneration models
- Bone regeneration models
- Tendinopathy / tendon injury models
Selected service packages:
Our array of services encompasses:
- consulting on potential applications of your technology in the field of musculoskeletal medicine
- advising on market opportunities and therapeutic needs
- consulting / developing project designs
- preparing animal protocols
- creating in-vitro and in-vivo models
- conducting preclinical in vitro and in vivo experiments
- determination of transduction/transfection using cartilage cells, synovium cells, bone cells, tendon cells from various species -including human cells
- proof-of-concept studies, biodistribution studies, pharmacokinetics, safety evaluation, efficacy studies
- providing a comprehensive portfolio of established animal models as well as in-vitro modeling systems
- detailed data analysis
- data reporting
We possess unparalleled expertise regarding the following target tissues/organs:
- joints
- cartilage
- bone
- tendon
- muscle
- intervertebral disc
We employ a variety of experimental methods, such as:
- creation of sophisticated, valid, and reliable research models (in vitro and in vivo)
- use of surgical and non-surgical animal models (small and large)
- precise and reproducible surgical procedures
- local and systemic administration of viral and non-viral vectors
- in depths analysis of on-target and off-target cells and tissues
- optimized cell isolation and purification
- DNA/RNA extraction
- Polymerase Chain Reaction (PCR)
- Next Generation Sequencing (NGS)
- histological evaluation, histopathology
- immunohistochemistry
- histomorphometry
- various imaging techniques: IVIS, x-ray, CT, MRI
- biomechanical testing
- behavioral tests: pain evaluation, gait analysis
- scoring/assessment: images, behaviour
Contact us for further details regarding our continuously expanding services.
Musculoskeletal Diseases
The disorders listed below provide valuable insight into the numerous unmet treatment needs within musculoskeletal diseases. Please don't hesitate to contact us for in-depth discussions about target diseases, areas of research interests, and how Lunatum Biotech can offer support in developing cures for these conditions. We are deeply committed to collaborating with you to make significant strides in the field of musculoskeletal medicine.
Joints and Rheumatic Joint Disorders
Osteoarthritis, Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
Cartilage
Osteoarthritis, cartilage defects, osteochondral defects, Diastrophic Dysplasia
Bone
Osteoporosis, Osteogenesis Imperfecta (OI), Fibrous Dysplasia, Hypophosphatasia, Fibrodysplasia Ossificans Progressiva (FOP), Multiple Epiphyseal Dysplasia (MED), Osteonecrosis, bone tumors, bone metastasis, bone fractures, osseous non-unions, bone defects
Tendon and Ligament
Tendon ruptures, Tendinitis, Tendinopathy, chronic tendon degeneration, ligament tears
Muscle and Rheumatic Muscle Diseases
Sarcopenia, Duchenne Muscular Dystrophy, Myasthenia Gravis, Spinal Muscular Atrophy, Polymyalgia Rheumatica, Polymyositis, muscle injuries
Intervertebral Disc
Intervertebral Disc Disease