Welcome to
Lunatum Biotech
The preclinical Contract Research Organization (CRO) for musculoskeletal gene medicine
Our Services
Lunatum Biotech is your reliable and innovative partner for preclinical research and development in the field of molecular musculoskeletal medicine. Our scientists use optimized techniques and work protocols for the isolation and in-depth analysis of on-target and off-target cells. Using a variety of innovative in-vitro modeling systems and in-vivo models, we provide crucial preclinical insights to companies working towards developing targeted genetic drugs for the rapidly expanding orthopedic gene therapy market.
The services of Lunatum Biotech:
- Consulting on potential applications of your technology in the field of musculoskeletal medicine
- Advising on market opportunities and therapeutic needs
- Consulting on project designs
- Preparing animal protocols
- Conducting preclinical in vitro and in vivo experiments
- Providing a comprehensive portfolio of established animal models as well as in-vitro modeling systems
- detailed data analysis
- data reporting
We have exceptional expertise with respect to the following target tissues/organs:
- bone
- cartilage
- tendon
- ligament
- joints
- muscle
- intervertebral disc
Our experimental work methods include:
- local and systemic administration of viral and non-viral vectors
- targeting and gene expression assays
- evaluation of tissue and cell specific transduction efficiency in vitro and in vivo
- in vivo targeting/tropism experiments
- in vivo efficacy studies
- use of surgical and non-surgical animal models (small and large)
- analysis of on-target and off-target cells and tissues
- optimized cell isolation and purification
- DNA/RNA extraction
- Polymerase Chain Reaction (PCR)
- Next Generation Sequencing (NGS)
- histological evaluation
- immunohistochemistry
- histomorphometry
- various imaging techniques
- biomechanical testing
Contact us for further details regarding our continuously expanding services.
Musculoskeletal Diseases
Bone
Osteoporosis, Osteogenesis Imperfecta (OI), Fibrous Dysplasia, Hypophosphatasia, Fibrodysplasia Ossificans Progressiva (FOP), Multiple Epiphyseal Dysplasia (MED), Osteonecrosis, bone tumors, bone metastasis, bone fractures, osseous non-unions, bone defects
Cartilage
Osteoarthritis, cartilage defects, osteochondral defects, Diastrophic Dysplasia
Tendon and Ligament
Tendon ruptures, Tendinitis, chronic tendon degeneration, ligament tears
Joints and Rheumatic Joint Disorders
Osteoarthritis, Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
Muscle and Rheumatic Muscle Diseases
Sarcopenia, Duchenne Muscular Dystrophy, Myasthenia Gravis, Spinal Muscular Atrophy, Polymyalgia Rheumatica, Polymyositis, muscle injuries
Intervertebral Disc
Intervertebral Disc Disease
The above listed disorders are just a few examples to show the significance of musculoskeletal medicine. Contact us for further discussions about target diseases and scientific fields of interest.